Assessment of Health Care Exposures and Outcomes in Adult Patients With Sepsis and Septic Shock
Katherine Fay and Coauthors
JAMA Network Open | Original Investigation, July 7, 2020
Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia coli, and the Need for Novel Prevention Strategies
Barbara J. Stoll and Coauthors
JAMA Pediatrics | Original Investigation, May 4, 2020
Prevalence of Antibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use
Chanu Rhee and Coauthors
JAMA Network Open | Original Investigation, April 16, 2020
Association of a Care Bundle for Early Sepsis Management With Mortality Among Patients With Hospital-Onset or Community-Onset Sepsis
Jonathan D. Baghdadi and Coauthors
JAMA Internal Medicine | Original Investigation, April 6, 2020
How Effective Is the Early Management Bundle for Severe Sepsis/Septic Shock?
Hannah Moreira and Richard Sinert
JAMA Internal Medicine | Invited Commentary, April 6, 2020
Risk Factors for Long-term Mortality and Patterns of End-of-Life Care Among Medicare Sepsis Survivors Discharged to Home Health Care
Katherine R. Courtright and Coauthors
JAMA Network Open | Original Investigation, February 26, 2020
Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial
François Lamontagne and Coauthors
JAMA | Original Investigation, February 12, 2020
Evaluation of the Coverage of 3 Antibiotic Regimens for Neonatal Sepsis in the Hospital Setting Across Asian Countries
Julia A. Bielicki and Coauthors
JAMA Network Open | Original Investigation, February 12, 2020
Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial
Steven Y. C. Tong and Coauthors
JAMA | Original Investigation, February 11, 2020
C-Reactive Protein Testing in Late-Onset Neonatal Sepsis: Hazardous Waste
Joseph B. Cantey and Charlene R. Bultmann
JAMA Pediatrics | Editorial, February 3, 2020
Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial
Tomoko Fujii and Coauthors
JAMA | Preliminary Communication, January 17, 2020
Lack of Benefit of High-Dose Vitamin C, Thiamine, and Hydrocortisone Combination for Patients With Sepsis
Andre C. Kalil
JAMA | Editorial, January 17, 2020
Differences in Central Line–Associated Bloodstream Infection Rates Based on the Criteria Used to Count Central Line Days
David Scheinker and Coauthors
JAMA | Research Letter, January 14, 2020
Evaluation of Plasma Microbial Cell-Free DNA Sequencing to Predict Bloodstream Infection in Pediatric Patients With Relapsed or Refractory Cancer
Kathryn P. Goggin and Coauthors
JAMA Oncology | Brief Report, December 19, 2019
Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial
Pierre-Francois Laterre and Coauthors
JAMA | Original Investigation, October 2, 2019
Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial
Alpha A. Fowler III and Coauthors
JAMA | Preliminary Communication, October 1, 2019
Is High-Dose Vitamin C Beneficial for Patients With Sepsis?
Emily B. Brant and Derek C. Angus
JAMA | Editorial, October 1, 2019
Incidence of Maternal Sepsis and Sepsis-Related Maternal Deaths in the United States
Matthew K. Hensley and Coauthors
JAMA | Research Letter, September 3, 2019
Association of Use of the Neonatal Early-Onset Sepsis Calculator With Reduction in Antibiotic Therapy and Safety: A Systematic Review and Meta-analysis
Niek B. Achten and Coauthors
JAMA Pediatrics | Original Investigation, September 3, 2019
Neonatal Sepsis Evaluation: Facing the Certainty of Uncertainty
Karen M. Puopolo and Gabriel J. Escobar
JAMA Pediatrics | Editorial, September 3, 2019
Cost of Pediatric Severe Sepsis Hospitalizations
Erin F. Carlton and Coauthors
JAMA Pediatrics | Research Letter, August 12, 2019
Long-term Host Immune Response Trajectories Among Hospitalized Patients With Sepsis
Sachin Yende and Coauthors
JAMA Network Open | Original Investigation, August 7, 2019
Association Between State-Mandated Protocolized Sepsis Care and In-hospital Mortality Among Adults With Sepsis
Jeremy M. Kahn and Coauthors
JAMA | Original Investigation, July 16, 2019
Wide Interest in a Vitamin C Drug co*cktail for Sepsis Despite Lagging Evidence
Rita Rubin
JAMA | Medical News & Perspectives, July 3, 2019
Risk Factors at Index Hospitalization Associated With Longer-term Mortality in Adult Sepsis Survivors
Manu Shankar-Hari and Coauthors
JAMA Network Open | Original Investigation, May 31, 2019
Recombinant Human Soluble Thrombomodulin in Patients With Sepsis-Associated Coagulopathy: Another Negative Sepsis Trial?
Tom van der Poll
JAMA | Editorial, May 19, 2019
New Phenotypes for Sepsis: The Promise and Problem of Applying Machine Learning and Artificial Intelligence in Clinical Research
William A. Knaus and Richard D. Marks
JAMA | Editorial, May 19, 2019
Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial
Jean-Louis Vincent and Coauthors
JAMA | Original Investigation, May 19, 2019
Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis
Christopher W. Seymour and Coauthors
JAMA | Original Investigation, May 19, 2019
Prevalence of Bacteremia and Bacterial Meningitis in Febrile Neonates and Infants in the Second Month of Life: A Systematic Review and Meta-analysis
Eric A. Biondi and Coauthors
JAMA Network Open | Original Investigation, March 22, 2019
Reducing Collateral Damage From Mandates for Time to Antibiotics in Pediatric Sepsis—Primum Non Nocere
Luregn J. Schlapbach and Coauthors
JAMA Pediatrics | Viewpoint, March 18, 2019
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial
Glenn Hernández and Coauthors
JAMA | Original Investigation, February 17, 2019
How Best to Resuscitate Patients With Septic Shock?
Derek C. Angus
JAMA | Editorial, February 17, 2019
Prevalence, Underlying Causes, and Preventability of Sepsis-Associated Mortality in US Acute Care Hospitals
Chanu Rhee and Coauthors
JAMA Network Open | Original Investigation, February 15, 2019
A Closer Look at Sepsis-Associated Mortality
Laura Evans
JAMA Network Open | Invited Commentary, February 15, 2019
Global Case-Fatality Rates in Pediatric Severe Sepsis and Septic Shock: A Systematic Review and Meta-analysis
Bobby Tan and Coauthors
JAMA Pediatrics | Original Investigation, February 11, 2019
Association of 30-Day Mortality With Oral Step-Down vs Continued Intravenous Therapy in Patients Hospitalized With Enterobacteriaceae Bacteremia
Pranita D. Tamma and Coauthors
JAMA Internal Medicine | Original Investigation, January 22, 2019
Effect of Levocarnitine vs Placebo as an Adjunctive Treatment for Septic Shock: The Rapid Administration of Carnitine in Sepsis (RACE) Randomized Clinical Trial
Alan E. Jones and Coauthors
JAMA Network Open | Original Investigation, December 21, 2018
Association of Corticosteroid Treatment With Outcomes in Adult Patients With Sepsis: A Systematic Review and Meta-analysis
Fang Fang and Coauthors
JAMA Internal Medicine | Original Investigation, December 21, 2018
Association Between Early Intravenous Fluids Provided by Paramedics and Subsequent In-Hospital Mortality Among Patients With Sepsis
Daniel J. Lane and Coauthors
JAMA Network Open | Original Investigation, December 14, 2018
Serum Creatinine in the Critically Ill Patient With Sepsis
Matthieu Legrand and John A. Kellum
JAMA | JAMA Diagnostic Test Interpretation, December 11, 2018
Artificial Intelligence Tools for Sepsis and Cancer
Jennifer Abbasi
JAMA | Biotech Innovations, December 11, 2018
Antibiotics for Sepsis—Finding the Equilibrium
Michael Klompas and Coauthors
JAMA | Viewpoint, September 14, 2018
Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries
Kristina E. Rudd and Coauthors
JAMA | Original Investigation, June 5, 2018
Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis
Idris V. R. Evans and Coauthors
JAMA | Original Investigation, July 24/31, 2018
Bundled Strategies for the Care of Children With Presumed Sepsis
Robert J. Vinci and Elliot Melendez
JAMA | Editorial, July 24/31, 2018
Defining Pediatric Sepsis
Luregn J. Schlapbach and Niranjan Kissoon
JAMA Pediatrics | Viewpoint, April 2018
Enhancing Recovery From Sepsis: A Review
Hallie C. Prescott and Derek C. Angus
JAMA | Review, January 2, 2018
Postsepsis Morbidity
Hallie C. Prescott and Derek C. Angus
JAMA | JAMA Patient Page, January 2, 2018
Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014
Chanu Rhee and Coauthors
JAMA | Original Investigation, September 13, 2017
Counting Sepsis, an Imprecise but Improving Science
Kristina E. Rudd and Coauthors
JAMA | Editorial, September 13, 2017
Epidemiology of Sepsis Among Adolescents at Community Hospital Emergency Departments: Implications for Rory’s Regulations
Idris V. R. Evans and Coauthors
JAMA Pediatrics | Research Letter, August 14, 2017
In Treating Sepsis, Questions About Timing and Mandates
Jennifer Abbasi
JAMA | Medical News & Perspectives, August 8, 2017
Association Between US Norepinephrine Shortage and Mortality Among Patients With Septic Shock
Emily Vail and Coauthors
JAMA | Original Investigation, April 11, 2017
A Quantitative, Risk-Based Approach to the Management of Neonatal Early-Onset Sepsis
Michael W. Kuzniewicz and Coauthors
JAMA Pediatrics | Original Investigation, April 2017
Association Between Early Lactate Levels and 30-Day Mortality in Clinically Suspected Sepsis in Children
Halden F. Scott and Coauthors
JAMA Pediatrics | Original Investigation, March 2017
Management of Sepsis and Septic Shock
Michael D. Howell and Andrew M. Davis
JAMA | JAMA Clinical Guidelines Synopsis, February 28, 2017
Surviving Sepsis Guidelines: A Continuous Move Toward Better Care of Patients With Sepsis
Daniel De Backer and Todd Dorman
JAMA | Viewpoint, February 28, 2017
Proportion and Cost of Unplanned 30-Day Readmissions After Sepsis Compared With Other Medical Conditions
Florian B. Mayr and Coauthors
JAMA | Research Letter, February 7, 2017
Association Between Early Lactate Levels and 30-Day Mortality in Clinically Suspected Sepsis in Children
Halden F. Scott and Coauthors
JAMA Pediatrics | Original Investigation, January 9, 2017
Economic Evaluation of Quality Improvement Interventions for Bloodstream Infections Related to Central Catheters: A Systematic Review
Teryl K. Nuckols and Coauthors
JAMA Pediatrics | Review, December 2016
Act Fast and Think Sepsis
JAMA | News From the Centers for Disease Control and Prevention, October 11, 2016
Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial
Didier Keh and Coauthors
JAMA | Original Investigation, October 3, 2016
Evaluating Glucocorticoids for Sepsis: Time to Change Course
Sachin Yende and B. Taylor Thompson
JAMA | Editorial, October 3, 2016
Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?
Peter Bentzer and Coauthors
JAMA | The Rational Clinical Examination, September 27, 2016
Practice Patterns and Outcomes Associated With Use of Anticoagulation Among Patients With Atrial Fibrillation During Sepsis
Allan J. Walkey and Coauthors
JAMA | Original Investigation, September 2016
Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial
Frank Bloos and Coauthors
JAMA Internal Medicine | Original Investigation, July 18, 2016
Effect of a Primary Care Management Intervention on Mental Health–Related Quality of Life Among Survivors of Sepsis: A Randomized Clinical Trial
Konrad Schmidt and Coauthors
JAMA | Original Investigation, June 28, 2016
Standardized Rehabilitation and Hospital Length of Stay Among Patients With Acute Respiratory Failure: A Randomized Clinical Trial
Peter E. Morris and Coauthors
JAMA | Original Investigation, June 28, 2016
The Challenging Task of Improving the Recovery of ICU Survivors
Shannon L. Goddard and Neill K. J. Adhikari
JAMA | Editorial, June 28, 2016
Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis
Lonneke A. van Vught and Coauthors
JAMA | Original Investigation, March 15, 2016
Immunosuppression and Secondary Infection in Sepsis: Part, Not All, of the Story
Derek C. Angus and Steven Opal
JAMA | Editorial, March 15, 2016
Sepsis and the Global Burden of Disease in Children
Niranjan Kissoon and Timothy M. Uyeki
JAMA Pediatriacs | Viewpoint, February 2016
Assessment of a Central Line–Associated Bloodstream Infection Prevention Program in a Burn-Trauma Intensive Care Unit
Lois Remington and Coauthors
JAMA Surgery | Research Letter, December 23, 2015
Association of Intensive Care Unit Admission With Mortality Among Older Patients With Pneumonia
Thomas S. Valley and Coauthors
JAMA | Original Investigation, September 22/29, 2015
Septic Shock: Advances in Diagnosis and Treatment
Christopher W. Seymour and Matthew R. Rosengart
JAMA | Review, August 18, 2015
Readmission Diagnoses After Hospitalization for Severe Sepsis and Other Acute Medical Conditions
Hallie C. Prescott and Coauthors
JAMA | Research Letter, March 10, 2015
Lactate in Sepsis
Hernando Gomez and John A. Kellum
JAMA | JAMA Diagnostic Test Interpretation, January 13, 2015
Sepsis Mandates: Improving Inpatient Care While Advancing Quality Improvement
Colin R. Cooke and Theodore J. Iwashyna
JAMA | Viewpoint, October 8, 2014
Hospital Deaths in Patients With Sepsis From 2 Independent Cohorts
Vincent Liu and Coauthors
JAMA | Research Letter, July 2, 2014
Mortality Related to Severe Sepsis and Septic Shock Among Critically Ill Patients in Australia and New Zealand, 2000-2012
Kirsi-Maija Kaukonen and Coauthors
JAMA | Original Investigation, April 2, 2014
Declining Case Fatality Rates for Severe Sepsis: Good Data Bring Good News With Ambiguous Implications
Theodore J. Iwashyna and Derek C. Angus
JAMA | Editorial, April 2, 2014
Guideline Promotes Early, Aggressive Sepsis Treatment to Boost Survival
Bridget M. Kuehn
JAMA | Medical News and Perspectives, March 13, 2013
Effect of Empirical Treatment With Moxifloxacin and Meropenem vs Meropenem on Sepsis-Related Organ Dysfunction in Patients With Severe Sepsis: A Randomized Trial
Frank M. Brunkhorst and Coauthors
JAMA | Original Contribution, June 13, 2012
Management of Sepsis: A 47-Year-Old Woman With an Indwelling Intravenous Catheter and Sepsis
Derek C. Angus
JAMA | Clinical Crossroads, April 13, 2011
Serial Evaluation of the SOFA Score to Predict Outcome in Critically Ill Patients
Flavio Lopes Ferreira and Coauthors
JAMA | Caring for the Critically Ill Patient, October 10, 2001